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Macfarlan Smith Ltd

Founded in 1815, Macfarlan Smith Limited is one of the world's oldest pharmaceutical companies, with almost 200 years of expertise in natural product extractions and chemical synthesis, specialising in opiate narcotics such as codeine and morphine.

Over the past two centuries, we have collaborated with Lord Lister, supplied chloroform to Sir James Simpson, and produced the first liquid essence of coffee. Today, as part of Johnson Matthey PLC’s Fine Chemicals Division, the company operates a state-of-the-art plant to the highest level of cGMP.

We are the world's leading manufacturer of opiate alkaloids and – together with our sister companies, Johnson Matthey Pharmaceutical Materials (NJ, USA) and Johnson Matthey Pharma Services (MA, USA) – we are able to provide the full spectrum of development, from drug discovery through to bulk production.